Climate change, together with other natural and human-made health stressors, influence human health and disease in numerous ways. Some existing health threats will intensify and new health threats will emerge. Not everyone is equally at risk. Important considerations include age, economic resources, and location. Preventive and adaptive actions, such as reducing the sources of global warming or setting up extreme weather early warning systems or improving water infrastructure, can reduce the severity of these impacts. Health effects of the disruption to the climate include respiratory and cardiovascular disease, injuries and premature deaths related to extreme weather, more widespread allergy symptoms, changes in the prevalence and geographical distribution of food- and waterborne illnesses and vector borne infectious diseases, and threats to mental health.