According to the Intergovernmental Panel on Climate Change, the effects of climate change on food security could be some of the most serious in the near-to-medium term, especially if global mean temperature increases by 3–4°C or more. In The Lancet, Marco Springmann and colleagues dig deeper, and report the most advanced projections so far of the effects of climate change on food and health for 155 regions in the year 2050. The researchers drew on a rich mixture of emission trajectories, socioeconomic pathways, and possible climate responses to model effects on global production, trade, and consumption.