The Climate Change and Human Health Literature Portal is a knowledge management tool for locating the most relevant scientific literature on the health implications of climate change. It provides access to a database of studies from around the world, published between 2007 and 2014. The National Institute of Environmental Health Sciences (NIEHS) developed the database as a technical input to the U.S. Global Change Research Program’s (www.globalchange.gov) Sustained Assessment process. The portal is an effort to make this database more accessible to a wider global audience, and to provide updates on a regular basis to further the study of climate impacts on human health.